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Further prospective clinical meta-analytic studies are needed to investigate

Le 23 juillet 2015, 04:35 dans Humeurs 0

BACKGROUND:: Traumatic brain injury (TBI) has been reported to be a common cause of benign paroxysmal positional vertigo (BPPV). However, only a few studies have investigated BPPV Nike Air Max Uk Cheap after TBI. The aim of this study was to identify the clinical characteristics of BPPV after TBI and to determine whether there are Nike Heel Trainers clinical differences between BPPV after TBI and idiopathic BPPV. Nike Men Blazer High METHODS:: The authors reviewed the medical records of 192 consecutive patients with positional vertigo after head injury during the period 2003 to 2009 and investigated 112 patients with idiopathic BPPV treated over the same period.

The clinical characteristics of BPPV after TBI and the clinical differences between the traumatic BPPV and idiopathic BPPV groups were investigated. RESULTS:: A total of 32 patients with... BPPV after TBI fulfilled the inclusion criteria. Twenty-four patients in the traumatic BPPV group Nike Shox Mens Shoes had posterior semicircular canal-BPPV and 11 patients lateral semicircular canal-BPPV. A total of 58 repositioning maneuver sessions were performed in these 32 patients.

Members of the traumatic BPPV group required more treatment sessions than members of the idiopathic group (p 0.05). CONCLUSIONS:: It is likely that BPPV after TBI is more difficult to treat than idiopathic BPPV, but no tendency to recur was observed in patients who developed BPPV after TBI compared with idiopathic BPPV. Further prospective clinical meta-analytic studies are needed to investigate the outcome of BPPV after TBI.

The latter is the active state for proton transfer to the semiquinone

Le 17 juillet 2015, 05:59 dans Humeurs 0

Structural features that have important implications for the fundamental process of transmembrane proton transfer are examined in the recently published high resolution atomic structures of the reaction center (RC) from Rhodobacter sphaeroides in the dark adapted state (DQ A Q B ) and the charged separated state (D + Q A Q B − ); the latter is the active state for proton transfer to the semiquinone. 

 

 

The structures Nike Shox R4 Women have been determined at 2.2 Å and 2.6 Å Nike Mens Shoes Uk resolution, respectively, as reported by Stowell et al. (1997) [Science 276: 812–816]. Three possible proton transfer pathways (P1, P2, P3) consisting of water molecules and/or protonatable residues were identified which connect the Q B binding region with the cytoplasmic exposed surface at Asp H224 & Asp M240 (P1), Nike Air Max Ltd Tyr M3 (P2) Mens Nike Air Force 1 Uk and Asp M17(P3). All three represent possible pathways for proton transfer into the RC. P1 contains an uninterrupted chain of water molecules. 

 

 

This path could, in addition, facilitate the exchange of quinone for quinol during the photocycle by allowing water to move into and out of the binding pocket. Located near these pathways is a cluster of electrostatically interacting acid residues (Asp-L213, Glu-H173, Asp-M17, Asp H124, Asp-L210 and Asp H170) each being within 4.5 Å of a neighboring carboxylic acid or a bridging water molecule. This cluster could serve as an internal ‘proton reservoir’ facilitating fast protonation of Q B − that could occur at a rate greater than that attainable by proton uptake from solution.

 

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Le 23 mars 2015, 10:31 dans Humeurs 0

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